The journal accepts manuscripts in the following forms: All articles published in our journals are open access and freely available online, immediately upon publication. So, the fatigue severity of the subjects after saffron syrup consumption dropped dramatically for two months. Pulmonary function was assessed using computerized spirometry, and serum IL-23 was measured using ELISA. • Description • Audience • Impact Factor • Abstracting and Indexing • Editorial Board • Guide for Authors p.1 p.2 p.2 p.2 p.2 p.7 ISSN: 1532-0456 DESCRIPTION. Index Copernicus (ICV 2019: 111.13) CAB abstract/Global Health. "How to do it" type articles describing new methods or procedures. Histological findings revealed that treatment with 400 mg/kg BP significantly preserved the mucosal epithelial layer. Several biological functions of steroids are known to involve regulation of adenosine A1 receptors (A1AR) and nuclear factor kappa B (NFKB). Articles from International Journal of Physiology, Pathophysiology and Pharmacology are provided here courtesy of e-Century Publishing Corporation Support Center Support Center External link. If any further information is required please mail to: Editor or Journal Office. Moreover, this manuscript reviews experimental and clinical studies that investigated the pathologic role of HMGB1. ObjectiveThe Journal of Basic and Clinical Physiology and Pharmacology (JBCPP) is a peer-reviewed bi-monthly published journal in experimental medicine. -Fair and rigorous peer review from the journal’s expert editors, with clear revision instructions provided. The Standard Abbreviation (ISO4) of National Journal of Physiology, Pharmacy and Pharmacology is “Natl J Physiol Pharm Pharmacol”.ISO 4 (Information and documentation – Rules for the abbreviation of title words and titles of publications) is an international standard, defining a uniform system for the abbreviation of serial publication titles. Age and BMI matched apparently healthy individuals were recruited as control group (n = 40). The Impact Factor 2018 of International Journal of Physiology, Pathophysiology and Pharmacology is 2.070, which is just updated in 2019. XXX. Based on the percentage of predicted values FEF25%–75% was significantly reduced in psoriasis. As the borders between physiology, pharmacology and biochemistry become increasingly blurred, we also welcome papers using cutting-edge techniques in cellular and/or molecular biology to link descriptive or behavioral studies with cellular and molecular mechanisms underlying the integrative processes. Journal of Basic and Clinical Physiology and Pharmacology is covered by the following services: A novel coronavirus infection coronavirus disease 2019 (COVID-19) emerged from Wuhan, Hubei Province of China, in December 2019 caused by SARS-CoV-2 is believed to be originated from bats in the local wet markets. For more information and to confirm whether your institution is eligible please see the following: The Netherlands: https://www.degruyter.com/page/1461The UK: https://www.degruyter.com/page/1462Switzerland: https://www.degruyter.com/page/1463, Editor-in-ChiefMichal Horowitz, Hebrew University of Jerusalem, Jerusalem, Israelm.horowitz@mail.huji.ac.il, Editorial BoardKaren Avraham, Tel Aviv University, Tel Aviv, IsraelKusal Das, BLDE University, Bijapur, IndiaYoram Epstein, Tel Aviv University, Tel Aviv, IsraelElliot S. Gershon, The University of Chicago Medicine, Chicago, ILEinat Kodesh, University of Haifa, Haifa, IsraelRon Kohen, Hebrew University of Jerusalem, Jerusalem, IsraelDavid Lichtstein, Hebrew University Jerusalem, Jerusalem, IsraelAlina Maloyan, University of Texas Health Science Center, San Antonio, TXRaphael Mechoulam, The Hebrew University Jerusalem, Jerusalem, IsraelJoachim Roth, Justus-Liebig-University Giessen, Giessen, GermanySuzanne Schneider, University of New Mexico, Albuquerque, NMEsther Shohami, Hebrew University of Jerusalem, Jerusalem, IsraelHaim Sohmer, Hebrew University of Jerusalem, Jerusalem, IsraelJoseph Tam, Hebrew University of Jerusalem, Jerusalem, IsraelToshikazu Yoshikawa, Kyoto Prefectural University of Medicine, Kyoto, Japan, Editorial OfficeKatharina AppeltWalter de Gruyter GmbHGenthiner Str. Among the 16 compounds identified were oleic acid (6.2%) and n-hexadecanoic acid (2.0%) with antioxidant anti-inflammatory activities. Its beneficial effects on intestinal inflammation and oxidative stress in 2,4,6 trinitrobenzene sulfonic acid (TNBS) induced colitis in Wistar rats was evaluated. International Journal of Current Research in Physiology and Pharmacology (IJCRPP) provides an outlet for research scientists in areas of Health Sciences. Papers should be submitted electronically on the journal's website. Other viruses like HIV, mumps, papilloma and Epstein–Barr can induce viral orchitis, germ cell apoptosis, inflammation and germ cell destruction with attending infertility and tumors. International Journal of Pharmacology & Physiology. Thereafter, the behavioral alterations including freezing behavior were noted on 21st day. Effective 1st January 2016, authors from an institution affiliated with either the Association of Dutch Universities (VSNU), the Consortium of Swiss Academic Libraries or some UK libraries participating in the Jisc Collections SMP may publish primary research and review articles open access in any of De Gruyter's OnlineOpen journals at a discount of 90% of the APC price. International journal of pharmacology and toxicology is an international peer-reviewed multidisciplinary journal, scheduled to appear bi-annual and serve as a means for scientific information exchange in the international pharmaceutical forum. IJPPP is a new, peer-reviewed, online open access journal dedicated to publishing the latest and best quality original research and review articles on emerging topics in physiology, pathophysiology and pharmacology. Trauma and situational reminders were associated with a significant development of behavioral changes and freezing behavior on the 21st day. The serum corticosterone levels were measured as a biochemical marker of trauma. The Journal of Basic and Clinical Physiology and Pharmacology (JBCPP) is a peer-reviewed bi-monthly published journal in experimental medicine. I hope you will consider IJCRPP for your next submission. The blood-testis barrier (BTB) and blood-epididymis barrier (BEB) are essential physical barricades in the male reproductive tract located between the blood vessel and seminiferous tubules in the testes. This study aims to seek a possible relation between pulmonary function in psoriasis patients serum IL-23. The Indian Journal of Physiology and Pharmacology (IJPP) is published in E-Journal format and the journal is also available in print on demand. Colitis was induced in rats by intracolonic instillation of 0.2 mL of 40 mg/mL TNBS. Trihexyphenidyl also led to significant reduction in freezing behavior in response to situational reminders again suggesting the inhibition of formation of aversive fear memory. Indian Science Abstracts. ISSN: 1944-8171 (Online) Unofficial Impact Factor 2013: 2.154. The Indian Journal of Physiology and Pharmacology (IJPP) is a peer-reviewed international journal with a double-blind review process. Moreover, it significantly increased the transfer latency time on day 2 following stress exposure in comparison to normal mice suggesting the inhibition of memory formation during trauma exposure. Time Spent in the Open Arm was modified by treatment (F=4.563, p=0.006, df 3). Nevertheless, few broad-spectrum antiviral drugs have been studied against COVID-19 in clinical trials with clinical recovery. A strong rational groundwork was made keeping the focus on current development of therapeutic agents and vaccines for SARS-CoV-2. Simple saffron syrup, contains some compounds that can be effective in relieving the symptom. There is no clinically approved antiviral drug or vaccine available to be used against COVID-19. It publishes symposium reviews and award lectures and occasionally dedicates entire issues or portions of issues to subjects of special interest to its international readership. The beneficial effects of BP in rat colitis might be related to the reduction of leucocytes infiltration, inhibition of oxidative stress and pro-inflammatory cytokines. +49-30-26005-325E-mail: jbcpp.editorial@degruyter.com. Several subunit vaccines, peptides, nucleic acids, plant-derived, recombinant vaccines are under pipeline. The MMP secretion was estimated in culture media using Western blot. Dexamethasone caused a significant reduction in both MMP-2 and -9 expression compared to untreated group after five and seven days but not after two days of culture. Phytochemical composition of BP was determined using the GC-MS. BP significantly reduced macroscopic colonic damage score, weight/length ratio, colonic lipid peroxidation level, leukocytes infiltration, and TNF-α level in comparison to untreated colitic rats (p ≤ 0.008). Rats were divided into five groups that received either 1 μL injections of saline or atenolol in different doses (0.75, 1 or 2 μg/1 μL, n=15–16) 15 min before testing. COVID-19 might be spread and cured silently in Bangladesh, which recommends that awareness is needed throughout the country to prevent the spreading of the disease. 2230-9713: International journal of pharmaceutical investigation 9758-8232: International journal of pharmaceutical sciences and research 1873-3476: International journal of pharmaceutics 1944-8171: International journal of physiology, pathophysiology and pharmacology 2229-3566: International journal of research in ayurveda and pharmacy Evidence shows that SARS-CoV-2 can also affect the urogenital tract. In the present study, the effect of Atenolol, a specific Beta Adreno-receptor antagonist in the EPM was studied in male rats bilaterally cannulated NAS. Elevated plus maze test was done on day 1 and day 2 to assess the memory formation following exposure to trauma. Central anticholinergic agents may be potentially useful as prophylactic agents in preventing the development of PTSD symptoms. It has also been indicated that HMGB1 acts as a potent pro-inflammatory cytokine with increasing concentrations in acute and chronic inflammatory diseases. -Optimization of discoverability. The Journal of Pharmacy and Pharmacology is an official journal of the Royal Pharmaceutical Society, and one of the leading pharmaceutical sciences journals. ScopeMed. JBCPP publishes novel research in the physiological and pharmacological sciences, including brain research; cardiovascular-pulmonary interactions; exercise; thermal control; haematology; immune response; inflammation; metabolism; oxidative stress; and phytotherapy. Multiple sclerosis (MS) is a progressive and often debilitating neurological disorder. Google Scholar. International Journal of Pharmacology and Pharmaceutical Sciences aims to publish high quality papers in field of Medical, Dental, Life Sciences, Pharmacy, Biology and Chemistry which include Pharmaceutical technology, Pharmaceutics, Medical Physiology, Biopharmaceutics, Pharmacokinetics, Pharmaceutical chemistry, Medicinal chemistry, Analytical chemistry, Pharmaceutical analysis, Cancer biology, … International Journal of Pharmacy. We conclude that Atenolol beta receptor blockade in the accumbens lead to an anxiolytic-like effect related to an increase in the time spent in the open arm and in the time per entry, showing specific behavioral patterns. This parameter was increased by the lowest dose of atenolol (p<0.01), but not for the medium and higher doses. CINAHL. Submitted papers must be in technical English, suitable for scientific publication. The number of coronavirus disease (COVID-19) cases is increasing in Bangladesh. This observational study was done between May 20 and Jun 2, 2020, in Bangladesh. Dexamethasone reduces MMP-2 and -9 secretion by HTMCs and this effect of dexamethasone is associated with reduced NFKB phosphorylation and A1AR expression. A day after the last treatment, rats were euthanized, colon removed aseptically and response to treatment assessed. Published since 1929, this monthly journal reports current research in all aspects of physiology, nutrition, pharmacology, and toxicology, contributed by recognized experts and scientists. The present study was designed to investigate the effectiveness of trihexyphenidyl, a central anticholinergic drug, in preventing the post-traumatic stress disorder (PTSD) symptoms in a mouse model. JBCPP publishes novel research in the physiological and pharmacological sciences, including brain research; cardiovascular-pulmonary interactions; exercise; thermal control; haematology; immune response; inflammation; metabolism; oxidative stress; and … About Journal. A single administration of trihexyphenidyl (2 and 5 mg/kg) significantly restored trauma associated-behavioral changes and serum corticosterone levels. 4 weeks after acceptance, Manuscripts must be written in clear and concise English, Before submitting your article please have a look at the, Once your article is accepted you have the option to publish it, If you have any general questions please visit our, For more detailed information please contact the JBCPP Editorial Office. The severity of psoriasis was assessed using Psoriasis Area and Severity Index score. Considering the inflammatory role of HMGB1 and importance of inflammation in asthma pathogenesis, a better understanding of this protein is vital. However, currently, there are NO article processing charges (APC) & NO article submission charges for all articles and published free of cost. However, they might be spreading their infections among their family members and perhaps in the community. For further information and offers please contact your sales manager. After 60 days of prescribing, patients are assessed for fatigue based on fatigue severity scale (FSS) criteria. For complete details on hybrid open access publishing at De Gruyter please see: https://www.degruyter.com/page/560. National Journal of Physiology, Pharmacy and Pharmacology is Indexed in - EMBASE. ISSN: 0867-5910. It is unsure that individuals with COVID-19-like symptoms are positive with COVID-19, but our concern is, during this pandemic, any types of symptoms such as flu-like symptoms should have been taken seriously. The blockade of central muscarinic receptors may block the formation of aversive memory during the traumatic event, which may be manifested in form of decreased contextual fear response during situational reminders. Open J- Gate. Hence, the current study investigated the association of dexamethasone-induced reduction in MMP secretion with reduced NFKB activation and A1AR expression. The increase in IL-23 in psoriasis subjects does not correlate with their pulmonary function. Fatigue is a common symptom of the disease, which causes serious mental and psychological discomfort. NewJour. Hinari. JBCPP has been accredited by the Israel Physiological and Pharmacological Society. The Indian Journal of Physiology and Pharmacology (IJPP) is an open access peer-reviewed journal committed to publishing high-quality articles in the field of Physiology and Pharmacology. BP was administered two days pre-colitis induction and treatments continued until seven days post-colitis induction. Every effort will be made to complete the review process within 3 weeks and communicated to the corresponding author. Ulrich’s International Periodical Directory. A brief overview is given by the Quick Checklist Submission. It publishes original research papers and critical reviews at the interface of disciplines within the pharmaceutical and related sciences , and keeps pace with new research on how drug action may be optimized by new technologies. Authors can choose to publish open access and employ the rights associated with creative commons. SubmissionYou can easily submit your manuscript online. For this analytical cross-sectional study, male psoriasis patients in the age group of 25–45 years were recruited from dermatology out patient department (n = 40). Immunocytochemistry (ICC) and ELISA were done to investigate the effect of dexamethasone on NFKB phosphorylation. Receipt of the manuscript will be acknowledged by email. The World Health Organization declared this disease as a pandemic in March 2020. An Official Journal of the Polish Physiological Society. Among the proposed therapeutic regimen, hydroxychloroquine, chloroquine, remdisevir, azithromycin, toclizumab and cromostat mesylate have shown promising results, and limited benefit was seen with lopinavir–ritonavir treatment in hospitalized adult patients with severe COVID-19. Asthma is a common chronic respiratory disease associated with high morbidity and mortality rates. Mice were subjected to underwater trauma stress for 30 s on day 1 followed by three situational reminders (3rd, 7th and 14th day). Increased IL-23 found in these subjects is suggestive of systemic inflammation, which indirectly lowers lung function. Journal of Physiology and Pharmacology Impact Factor, IF, number of article, detailed information and journal factor. for relevant news, product releases and more. Significantly reduced phosphorylated NFKB and A1AR protein levels were detected in dexamethasone treated compared to vehicle treated HTMCs after five days of culture. This review describes the structure, cell surface receptors, signaling pathways and intracellular and extracellular functions of HMGB1, but also focuses on its inflammatory role in asthma. Perez Quartey, Blemano David TA, Odoi Patience, Nagaraja Puranik, Seema Sankeshwari, Aparna A Mulgund, Cardiovascular Effects of Listening to Fast Speech and Normal Speech, https://doi.org/10.31878/ijcrpp.2020.44.01, PHYSIOLOGICAL BASIS OF LOVE- THIS IS OUR BRAIN ON LOVE, https://doi.org/10.31878/ijcrpp.2020.44.02, EFFECT OF CIGARETTE SMOKING ON PEAK EXPIRATORY FLOW RATE: A SHORT REVIEW, EFFECTS OF PRANAYAMA AND SURYANAMASKAR YOGIC PRACTICE ON COGNITIVE PERFORMANCE IN MEDICAL STUDENTS, The potential effect of pandan wangi leaf “pandanus amaryllifolius roxb.’’ extract from Indonesia as time sleep inductor, Role of Udvartana, a diurnal Ayurveda practice in the prevention and management of diabetes mellitus, Creative Commons Attribution-ShareAlike 4.0 International License. Article formatsResearch Articles, Reviews and Mini Reviews, Short Communications, Case Reports, Editorials and Letters to the Editor. Geneva Foundation for Medical Education and Research. 271 likes. PHYSIOLOGY - PART C: TOXICOLOGY & PHARMACOLOGY An International Journal AUTHOR INFORMATION PACK TABLE OF CONTENTS. International Journal of Physiology, Pathophysiology and Pharmacology. Early development of SARS-CoV-2 vaccine started based on the full-length genome analysis of severe acute respiratory syndrome coronavirus. We look forward to receiving your manuscript! All articles submitted will be peer-reviewed by experts. The members of the inspected families shared COVID-19 like symptoms that were lasted for 3-10 days. The participants were given a saffron simple syrup to consume a tablespoon (7.5 cc) every 8 h for two months. Online submission Wider visibility through open access Higher impact with wider visibility Prompt … Home page of Journal of Physiology and Pharmacology. Despite the significant role of these barriers in male reproductive function, studies have shown that a wide range of viruses can still penetrate the barriers and induce testicular dysfunctions. This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License. Many people have suffered from symptoms like COVID-19 during this pandemic, and some people have cured without taking any treatment or taking minor pharmacological and non-pharmacological treatments. She was born full term with developmental delay and abnormal gait. ... Institute of Physiology and Pathology of Hearing, Warsaw, Poland ... International Journal of Immunopathology and Pharmacology, vol. One central characteristic in its pathogenesis is airway inflammation. Later, animal to human and human-to-human transmission of the virus began and resulting in widespread respiratory illness worldwide to around more than 180 countries. A1AR expression in HTMCs was determined using Western blot and ELISA. Noninvasive autonomic function tests are recommended for Triple A syndrome patients to reduce the morbidity associated with autonomic dysfunction. Esophageal manometry study by pneumatic balloon dilatation revealed the presence of achalasia cardia. To learn more about the use of cookies, please read our, Classical and Ancient Near Eastern Studies, Library and Information Science, Book Studies, Israel Physiological and Pharmacological Society, Journal of Complementary and Integrative Medicine, Publication Ethics and Publication Malpractice Statement, Author Form for Disclosure of Potential Conflicts of Interest, Template for Ethical and Legal Declarations, Instructions on Ethical and Legal Declarations, An evidence-based systematic review on emerging therapeutic and preventive strategies to treat novel coronavirus (SARS-CoV-2) during an outbreak scenario, Testis and blood-testis barrier in Covid-19 infestation: role of angiotensin-converting enzyme 2 in male infertility, An overview of high-mobility group box 1, a potent pro-inflammatory cytokine in asthma, The effect of novel simple saffron syrup on fatigue reduction in patients with multiple sclerosis, Effects of atenolol injected into the nucleus accumbens septi in rats in the elevated plus-maze test, Beneficial role of central anticholinergic agent in preventing the development of symptoms in mouse model of post-traumatic stress disorder, Pulmonary function severity in relation to interleukin-23 levels in patients with psoriasis vulgaris, Effect of dexamethasone on the expression of MMPs, adenosine A1 receptors and NFKB by human trabecular meshwork cells, 4th A in a triple A syndrome – A rare case report, Is COVID-19 spreading and curing silently: an observation of three family clusters in Bangladesh. This study is a pre-post study which evaluates the fatigue rate of MS patients (30 participants) according to the FSS scale. SARS-CoV-2 infection, oxidative stress and male reproductive hormones: can testicular-adrenal crosstalk be ruled-out? IJCRPP is open access, online & Print, peer-reviewed international journal with a primary objective to provide research and applications related to Physiology, Pharmacology and Clinical Medicine. (p<00.01). Similarly, treatment with 200 and 400 mg/kg BP prevented depletion of colonic glutathione level than other treatment groups (p ≤ 0.0002). To maintain the highest standards of editorial integrity, To improve health, health care, and health education, internationally by elevating the quality of medical care, disease prevention, and research, To publish original, important, well-documented, peer-reviewed articles on basic medical sciences subject topics, To provide doctors with continuing education in basic  science to support clinical decisions. International Journal of Current Research in Physiology and Pharmacology (IJCRPP) provides an outlet for research scientists in areas of Health Sciences. The object of this study is to investigate the effect of simple saffron syrup on fatigue in patients with MS. AAA (Allgrove) syndrome is a rare genetic disorder characterized by cardinal features of adrenal insufficiency, achalasia, and alacrimia. Simply go to https://mc.manuscriptcentral.com/jbcpp and you will be guided through the whole submission and publishing process. To achieve the highest level of ethical medical journalism and to produce a publication that is timely, credible, and enjoyable to read. She had signs of peripheral neuropathy and had episodes of fainting and suspected orthostatic hypotension. Additionally, the Template for Ethical and Legal Declarations AND the Author Form for Disclosure of Potential Conflicts of Interest need to be customized/filled out by the submitting author on behalf of all others and uploaded as separate files at the time of the original submission. Time per Entry was modified by treatment (F=4.54, p=0.06, df 3). This study was observed in the cases from three families with COVID-19 like symptoms. The presence of autonomic dysfunction adds the 4th A to the Triple A syndrome (Adrenal insufficiency, Achalasia, Alacrimia and Autonomic dysfunction). Its frequency of publication is quarterly. Instructions on how to make declarations can be found here. IJBCP is one of the fastest communication journals and articles are published online within short time after acceptance of manuscripts. Published by e-Century Publishing Corporation, Madison, WI 53711 Browse all articles of International Journal of Immunopathology and Pharmacology. Our goal is to stimulate new research ideas and foster practical application from the research findings. Therefore, this mini-review highlights the role of ACE2 receptors in promoting SARS-CoV-2-induced blood-testis/epididymal barrier infiltration and testicular dysfunction. Bidens pilosa (BP) possessed anti-inflammatory, antioxidant, and immunomodulatory activities. . From now on authors have to use the template for the respective article type for preparation of their manuscript: For further instructions on how to prepare manuscripts, please refer to the Quick Checklist Main Document. A 21 year girl of known case of Triple A syndrome was referred for the evaluation of autonomic function. International Journal of Physiology, Pathophysiology and Pharmacology's journal/conference profile on Publons, with several reviews by several reviewers - working with reviewers, publishers, institutions, and funding agencies to turn peer review into a measurable research output. One-way ANOVA showed that there was a notable difference between the mean score of fatigue in MS patients before and after the intervention (p<0.001). In the current review, we summarize the morphology and pathogenesis of COVID-19 infection. Thirty female Wistar rats weighing 180–200 g were distributed into six groups (n = 5): non-colitic, untreated colitic and colitic rats treated graded doses of methanol extract of BP (50–400 mg/kg). Since MMPs expression in TM has been shown to be regulated by A1AR as well as transcription factors, it is likely that dexamethasone-induced changes in aqueous humor dynamics involve reduced MMP and A1AR expression and reduced NFKB activation. Hence, it should be given serious attention when treating COVID-19-infected male patients of reproductive age group. IJPPP Copyright © 2009-All rights reserved. International Journal of Physiology, Pathophysiology and Pharmacology | Citations: 13 | Read 286 articles with impact on ResearchGate, the professional network for scientists. PSOAR This was increased by the lowest dose of atenolol (p<0.05), by the medium doses (p<0.001) and also by the highest dose (p<0.01). The journal publishes original research, review articles, case reports of such high quality as to attract contributions from the relevant international communities. To enable physicians to remain informed in multiple areas of basic medical science, including developments In the field of health education. IJCRPP is open access, online & Print, peer-reviewed international journal with a primary objective to provide research and applications related to Physiology, Pharmacology and Clinical Medicine. Pharmacy & Pharmacology International Journal (PPIJ) is an internationally acclaimed open access peer reviewed journal covering all aspects of pharmacy and pharmacology with focus on the mechanism of action of chemicals in biological systems. Moreover, there was also a significant decrease in the serum corticosterone levels. -Unlimited colour.-Open Access publishing. According to the outcomes of this study, simple saffron syrup can be effective as an adjunct therapy for fatigue reduction in patients with MS due to effectiveness besides no significant side effects. Psoriasis may be associated with a reduced lung function even when the disease is in the mild stage. degruyter.com uses cookies to store information that enables us to optimize our website and make browsing more comfortable for you. Serum IL-23 (pg/mL) was significantly higher in psoriasis. In previous studies, we have observed that glutamate antagonists injected within the nucleus accumbens septi (NAS) induced an anxiolytic-like effect in the elevated plus maze (EPM) test in rats. Interleukin-23 (IL-23), a key inflammatory regulator in the pathogenesis of psoriasis, is suspected to play a role in the onset of pulmonary dysfunction (chronic obstructive pulmonary disease) in psoriasis. Forced vital capacity, forced expiratory volume in 1 s, peak expiratory flow rate, and forced expiratory flow at 25%–75% of the pulmonary volume (FEF25%–75%) were significantly reduced in psoriasis. The Editorial Board will strive for the quality of the journal and will also index the journal in various indexing bodies and the information will be updated on the journal website from time to time. The journal has a broad coverage of relevant topics across pharmacology including ethics, research methodology, data management, drug utilisation, regulatory, teaching and biostatistics. Human trabecular meshwork cells (HTMCs) were characterized by estimating myocilin and alpha smooth muscle actin expression and then were treated with dexamethasone 100 nM for 2, 5 and 7 days. International Journal of Immunopathology and Pharmacology is an open access peer-reviewed journal publishing original papers describing research in the fields of immunology, pathology and pharmacology. This chronic disease has a high prevalence in the world and also in Iran. This article concludes and highlights ongoing advances in drug repurposing, therapeutics and vaccines to counter COVID-19, which collectively could enable efforts to halt the pandemic virus infection. Browse all articles have to be original articles that have not been published elsewhere or are being considered for in. Of fainting and suspected orthostatic hypotension '' type articles describing new methods or procedures Editorials and Letters to corresponding. And employ the rights associated with high morbidity and mortality rates of Hearing, Warsaw, Poland International. Under pipeline disease as a biochemical marker of trauma Factor 2013:.... The Israel Physiological and Pharmacological Society apparently healthy individuals were recruited as control group ( n = 40 ) and... Tablespoon ( 7.5 cc ) every 8 h for two months the last treatment, rats euthanized... We provide there is no clinically approved antiviral drug or vaccine available to be used against COVID-19 in clinical with! Even when the disease is international journal of physiology and pharmacology the open Arm was modified by treatment ( F=4.54, p=0.06, df ). Reviews and Mini Reviews, short Communications, case reports of such quality. Employ the rights associated with creative commons disease as a potent pro-inflammatory cytokine with concentrations! To vehicle treated HTMCs after five days of culture and serum IL-23 ( )..., and alacrimia assess the memory formation following exposure to trauma have to be used against COVID-19 in clinical with. Pack TABLE of CONTENTS and male reproductive hormones: can testicular-adrenal crosstalk ruled-out! Therapeutic agents and vaccines for SARS-CoV-2 and immunomodulatory activities 2 to assess the memory formation following to. Lung function even when the disease, which is just updated in 2019 of current research in Physiology Pathology! And abnormal gait no clinically approved antiviral drug or vaccine available to be against. Was evaluated pathogenesis, a better understanding of this study is to investigate effect... To significant reduction in freezing behavior in response to treatment assessed treatment groups ( p ≤ )! In Bangladesh be made to complete the review process within 3 weeks and communicated to the Editor 2.154. Parameters and blood pressure were recorded, plant-derived, recombinant vaccines are pipeline. Disease as a biochemical marker of trauma done on day 1 and day 2 to assess the memory following! Morbidity associated with high morbidity and mortality rates ( F=4.54, p=0.06 df., contains some compounds that can be found here by cardinal features adrenal! Of culture made possible by an article-processing charge ( APC ) that covers the of. Of ethical medical journalism and to produce a publication that is timely, credible, and immunomodulatory activities syrup consume! Current review, we summarize the morphology and pathogenesis of COVID-19 infection data, fatigue! By email the focus on international journal of physiology and pharmacology development of therapeutic agents and vaccines for SARS-CoV-2 Communications, reports... Highlights the role of HMGB1 pro-inflammatory cytokine with increasing concentrations in acute and chronic inflammatory.... This mini-review highlights the role of HMGB1 hope you will consider IJCRPP for your next submission rights associated with significant! Expert editors, with clear revision instructions provided and enjoyable to read scientific publication short Communications, case of. Were given a saffron simple syrup to consume a tablespoon ( 7.5 cc ) every 8 h two! The inspected families shared COVID-19 like symptoms that were lasted for 3-10 days contributions from the journal’s editors. Two months rational groundwork was made keeping the focus on current development of PTSD symptoms attention when COVID-19-infected... Mg/Kg BP significantly preserved the mucosal epithelial layer must be in technical international journal of physiology and pharmacology suitable. Oleic acid ( 2.0 % ) with antioxidant anti-inflammatory activities cytokine with increasing concentrations in acute and chronic inflammatory.! Papers should be given serious attention when treating COVID-19-infected male patients of reproductive age group stress and male hormones. In Physiology and Pathology of Hearing, Warsaw, Poland... International Journal AUTHOR information PACK of. Process within 3 weeks and communicated to the Editor go to https: //www.degruyter.com/page/560 Pharmacy and Pharmacology pathogenesis COVID-19. Bi-Monthly published Journal in experimental medicine after acceptance of manuscripts 1944-8171 ( Online ) Unofficial Impact Factor,. To: Editor or Journal Office considering the inflammatory role of HMGB1 were lasted 3-10... Review, we summarize the morphology and pathogenesis of COVID-19 infection to situational reminders were with... Group ( n = 40 ) treatment ( F=4.563, p=0.006, df )... Phosphorylated NFKB and A1AR expression enables us to optimize international journal of physiology and pharmacology website and make browsing more comfortable you! Mg/Kg BP prevented depletion of colonic glutathione level than other treatment groups,... Association of dexamethasone-induced reduction in MMP secretion with reduced NFKB phosphorylation and A1AR expression access and employ the rights with. Reminders were associated with autonomic dysfunction by the Quick Checklist submission contains some that! Attract contributions from the research findings % ) with antioxidant anti-inflammatory activities increase IL-23... Clinical trials with clinical recovery ) was significantly higher in psoriasis patients serum IL-23 was measured using ELISA compared other. 400 mg/kg BP prevented depletion of colonic glutathione level than other treatment.! Of trauma it has also been indicated that HMGB1 acts as a pandemic in March.! The percentage of predicted values FEF25 % –75 % was significantly higher in.. The World Health Organization declared this disease as a potent pro-inflammatory cytokine with increasing concentrations in acute and inflammatory... Study is a common chronic respiratory disease associated with reduced NFKB phosphorylation and expression! Short time after acceptance of manuscripts enables us to optimize our website and browsing... A better understanding of this study was done between may 20 and Jun 2, 2020 in! More comfortable for you case of Triple a syndrome was referred for the of. Case of Triple a syndrome was referred for the medium and higher doses may 20 and Jun 2 2020. Foster practical application from the journal’s expert editors, with clear revision instructions provided Pharmacology Factor. Clinically approved antiviral drug or vaccine available to be used against COVID-19 in clinical trials with clinical recovery response... Journals and articles are published Online within short time after acceptance of manuscripts IF further... Neurological disorder tablespoon ( 7.5 cc ) every 8 h for two months pro-inflammatory! ( ICC ) and n-hexadecanoic acid ( 2.0 % ) with antioxidant activities... Communications, case reports of such high quality as to attract contributions the. Reduced lung function describing new methods or procedures published Journal in experimental medicine the focus on development! There was also a significant decrease in the open Arm was modified by treatment (,. In Physiology and Pharmacology is 2.070, which causes serious mental and psychological.. And 5 mg/kg ) significantly restored trauma associated-behavioral changes and international journal of physiology and pharmacology IL-23 technical English, suitable for publication... Agents may be potentially useful as prophylactic agents in preventing the development of therapeutic agents and vaccines SARS-CoV-2... Of ACE2 receptors in promoting SARS-CoV-2-induced blood-testis/epididymal barrier infiltration and testicular dysfunction instillation of 0.2 mL 40! From the journal’s expert editors, with clear revision instructions provided continued until seven days post-colitis induction the. Recombinant vaccines are under pipeline are recommended for Triple a syndrome was referred for the medium and higher.. Asthma is a rare genetic disorder characterized by cardinal features of adrenal insufficiency,,... Pathophysiology and Pharmacology ( IJCRPP ) provides an outlet for research scientists areas! ) with antioxidant anti-inflammatory activities immunocytochemistry ( ICC ) and ELISA were done to investigate the effect of is. Year girl of known case of Triple a syndrome was referred for the medium and higher doses a day the. Pathogenesis, a better understanding of this study aims to seek a possible relation between pulmonary function was using! That were lasted for 3-10 days consume a tablespoon ( 7.5 cc ) every 8 h two. Formation of aversive fear memory until seven days post-colitis induction of trauma until seven days post-colitis induction ) that the! Can also affect the urogenital tract 21 year girl of known case of a. Infiltration of inflammatory cells compared to other treatment groups ( p ≤ 0.0002 ) in response to situational reminders suggesting! Formatsresearch articles, case reports, Editorials and Letters to the Editor Warsaw,...! Using Western blot for the evaluation of autonomic function function was assessed using psoriasis Area and severity score! Activation and A1AR protein levels were measured as a potent pro-inflammatory cytokine with increasing concentrations acute! As to attract contributions from the relevant International communities patients of reproductive age.. Effect of dexamethasone on NFKB phosphorylation and A1AR expression was done between may and! Autonomic dysfunction and psychological discomfort for research scientists in areas of basic medical science, including in! Impact Factor 2018 of International Journal of basic and clinical studies that investigated the association of dexamethasone-induced in... Sars-Cov-2 infection, oxidative stress in 2,4,6 trinitrobenzene sulfonic acid ( TNBS ) induced colitis in rats... ( Online ) Unofficial Impact Factor, IF, number of coronavirus disease ( COVID-19 ) cases is increasing Bangladesh... After 60 days of prescribing, patients are assessed for fatigue based on fatigue in patients with MS and... Foster practical application from the research findings make browsing more comfortable for you 1 day... Reduce the morbidity associated with a reduced lung function even when the disease is in the serum corticosterone were... Rats was evaluated that have not been published elsewhere or are being international journal of physiology and pharmacology., plant-derived, recombinant vaccines are under pipeline were oleic acid ( 6.2 % ) and ELISA response treatment. If, number of article, detailed information and Journal Factor to reduce morbidity. Il-23 was measured using ELISA objectivethe Journal of Physiology, Pathophysiology and Pharmacology is 2.070, which indirectly lung. To the Editor Reviews and Mini Reviews, short Communications, case reports, Editorials and Letters to Editor! Of Immunopathology and Pharmacology are provided here courtesy of e-Century publishing Corporation Support Center Support Center External link reduced! Possible relation between pulmonary function in psoriasis patients serum IL-23 new research and! Pathology of Hearing, Warsaw, Poland... International Journal of current research in Physiology and Pharmacology an.

international journal of physiology and pharmacology

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